Cultrex® Basement Membrane Extract (BME) is a soluble form of basement membrane purified from Engelbreth-Holm-Swarm (EHS) tumor. This extract provides a natural extracellular matrix hydrogel that polymerizes at 37°C to form a reconstituted basement membrane. Basement membranes are continuous sheets of specialized extracellular matrix that form an interface between endothelial, epithelial, muscle, or neuronal cells and their adjacent stroma and that play an essential role in tissue organization by influencing cell adhesion, migration, proliferation, and differentiation. The major components of BME include laminin, collagen IV, entactin, and heparin sulfate proteoglycans.
The Cultrex® BME Cell Invasion Assay provides a tool for assessing cell invasion through a reconstituted basement membrane and is available in 24 and 96 well formats.
Material Safety Data Sheet(s)
msds_3455-096-02 5X BME Solution
msds_3455-096-05 10X Cell Dissociation Solution
msds_3455-096-04 25X Cell Wash Buffer
msds_3455-096-03 10X Coating Buffer
msds_4892-010-01 Calcein AM
3455-024-01 Safety Data Sheets are not provided for “articles” defined as a manufactured item other than a fluid or particle.
3455-096-01 Safety Data Sheets are not provided for “articles” defined as a manufactured item other than a fluid or particle.
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