PARG Homogeneous Inhibition Assay Kit

$533.00

The PARG Homogeneous Inhibition Assay Kit is for the high-throughput in vitro screening of candidate PARG inhibitors and determination of IC50 values.

Contract Services are also available.

Available Size(s): 96 tests Catalog Number: 4691-096-K Category:

Description

This homogeneous assay couples PARG hydrolysis of PAR polymer to a light generating luciferase assay. Inhibitors are identified by a decrease in luminescent signal when PARG activity is inhibited.

FEATURES:

  • Rapid 30-minute assay
  • Homogeneous assay – No wash steps
  • Highly sensitive luminescent assay, detects as little as 10% PARG inhibition

APPLICATIONS:
For the screening of candidate PARG inhibitors and determination of IC50 values.

Protocol(s)

protocol_4691-096-K

Material Safety Data Sheet(s)

msds_4691-096-01 PARG Enzyme 100 mU per

msds_4691-096-02 10X PARG Dilution Buffer

msds_4691-096-03 D-Luciferin

msds_4691-096-04 Luciferase Cycling Enzymes

msds_4691-096-05 10X dCTP

msds_4691-096-06 PARG Substrate

msds_4691-096-07 Cycling Buffer

4691-096-P Safety Data Sheets are not provided for “articles” defined as a manufactured item other than a fluid or particle.

Catalog # 4691-096-K includes :
Catalog Number Description Qty
4691-096-07 Cycling Buffer 1
4691-096-P 96 Well White Round Bottom Plate 1
4691-096-01 PARG Enzyme, 100 mU/µL 1
4691-096-02 10X PARG Dilution Buffer 1
4691-096-03 D-Luciferin 1
4691-096-04 Luciferase Cycling Enzymes 1
4691-096-05 10X dCTP 1
4691-096-06 PARG Substrate 1