Material Safety Data Sheet(s)
Trevigen offers several types of controls to develop familiarity with the methods of in situ apoptosis labeling and to determine if reagents are working optimally.
TACS-Nuclease™ is a novel DNA endonuclease that is used to prepare a positive control from your own samples. The nuclease can simply be added to the labeling reaction mixture or if preferred in a separate step. DNA fragments formed by the action of this enzyme serve as substrates for labeling, producing a positive signal in virtually every cell and demonstrating adequate permeabilization.