Calcein AM (structure A) is a non-fluorescent, hydrophilic compound that easily permeates intact, live cells. The hydrolysis of Calcein AM by intracellular esterases produces calcein (structure B), a hydrophilic, strongly fluorescent compound that is well-retained in the cell cytoplasm. Cells grown in black-walled plates can be stained and quantified in less than two hours.
- Molecular weight: 995
- Presentation: 50 μg dessicated pellet
- Soluble in DMSO
Part of below kit(s)
Material Safety Data Sheet(s)
msds_4892-010-01 Calcein AM
Metastasis Suppressors Regulate the Tumor Microenvironment by Blocking Recruitment of Prometastatic Tumor-Associated Macrophages
Casey Frankenberger, Daniel Rabe, Russell Bainer, Devipriya Sankarasharma, Kiran Chada, Thomas Krausz, Yoav Gilad, Lev Becker, and Marsha Rich Rosner
Cancer Res., Oct 2015; 75: 4063 – 4073.