Physiologic Cell Culture

2D and 3D Cell Culture and In Vivo
Trevigen’s products for physiologic cell culture recreate tissue microenvironments to elicit in vivo structure and function for cells in vitro. These tools for 2D and 3D cell culture are designed, developed, produced, qualified, and supported by our Cultrex® laboratory staff. Our products include alternatives to Matrigel® or Geltrex®, including several unique types of Basement Membrane Extract (BME) matrix containing different compositions of extracellular matrix (ECM) proteins. These matrices are qualified for specific applications, such as 3D, stem cell, spheroid, and organoid cultures. Other purified ECM proteins offered include Laminin I, Collagen I, Collagen IV, Vitronectin and Fibronectin, as well as the poly-amino acids Poly-D-Lysine, Poly-L-Lysine and Poly-L-Ornithine; there is also a selection of ECM-coated labware.  Cultrex® assay kits provide rapid and reproducible results for cell invasion, migration, proliferation and viability, as well as for angiogenesis, embryoid body formation, and spheroid formation, proliferation and invasion. Trevigen’s organoid culture products provide a selection of mouse and human organoid progenitor cells as well as organoid-qualified basement membrane matrices for intestinal, liver, colon, pancreatic and breast organoids. These Trevigen products are widely used in cancer research, regenerative medicine, stem cell research and genetic toxicology.

Matrigel is a registered trademark of Corning Incorporated. Geltrex is a registered trademark of Invitrogen Corporation.

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