Anti-Bax

The Bcl-2 family of proteins plays a crucial role in the regulation of cell death in many eukaryotic systems. Bax has been shown to redistribute from the cytosol to the mitochondria during apoptosis, and overexpression of Bax can accelerate cell death. Coregulation of Bax dimer formation and intracellular localization are associated with Bax conformational changes.

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